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Writer's pictureNadene Barker

Understanding Mood Stabilizers: A Guide for Patients

Mood stabilizers are essential medications for individuals with mood disorders, such as bipolar disorder, schizoaffective disorder, and certain forms of depression. These medications help regulate mood swings, prevent extreme highs and lows, and maintain emotional stability. If you or a loved one has been prescribed mood stabilizers, it's important to understand how they work, their benefits, potential side effects, and the importance of adherence to your treatment plan.


How Mood Stabilizers Work

Mood stabilizers work by balancing neurotransmitters in the brain, which are chemicals that transmit signals between nerve cells. These medications help to stabilize mood by reducing the frequency and severity of mood swings. They are particularly effective in managing manic and hypomanic episodes, as well as preventing depressive episodes in bipolar disorder.

Types of Mood Stabilizers

There are several types of mood stabilizers, each with different mechanisms of action:

  1. Lithium: Lithium is one of the oldest and most effective mood stabilizers. It helps to reduce mania and prevent recurrence of mood episodes. Regular blood tests are required to monitor lithium levels and prevent toxicity.

  2. Anticonvulsants: These medications are also used to treat epilepsy but have mood-stabilizing effects. Examples include:

  • Valproate (Depakote): Effective in treating mania and preventing mood swings.

  • Lamotrigine (Lamictal): Particularly useful in preventing depressive episodes.

  • Carbamazepine (Tegretol): Used for acute mania and maintenance therapy.

  1. Atypical Antipsychotics: Some antipsychotic medications also have mood-stabilizing properties and are used in combination with other mood stabilizers. Examples include:

  • Olanzapine (Zyprexa)

  • Risperidone (Risperdal)

  • Quetiapine (Seroquel)

Benefits of Mood Stabilizers

  • Symptom Control: Mood stabilizers can significantly reduce the intensity and frequency of mood swings.

  • Prevention of Episodes: Regular use of these medications helps prevent the recurrence of manic, hypomanic, and depressive episodes.

  • Improved Functioning: With mood stabilization, individuals often experience better functioning in daily activities, relationships, and work.

Potential Side Effects

While mood stabilizers can be highly effective, they may also cause side effects. Common side effects include:

  • Nausea and Vomiting: These can occur, particularly when starting the medication.

  • Weight Gain: Some mood stabilizers can increase appetite, leading to weight gain.

  • Drowsiness: Sedation is a common side effect, especially with lithium and anticonvulsants.

  • Tremors: Fine hand tremors can occur with lithium.

  • Increased Thirst and Urination: Particularly with lithium, this requires maintaining adequate hydration.

Managing Side Effects

If you experience side effects, it's important to discuss them with your healthcare provider. They can adjust the dosage, switch medications, or suggest ways to manage side effects. Never stop taking your medication without consulting your provider, as this can lead to a relapse of symptoms.

The Importance of Adherence

Adhering to your prescribed medication regimen is crucial for managing your condition effectively. Here are some tips to help you stay on track:

  • Set Reminders: Use alarms, apps, or pill organizers to remind you to take your medication.

  • Educate Yourself: Understanding your medication and how it helps can motivate you to stick with your treatment.

  • Communicate: Keep an open line of communication with your healthcare provider about any concerns or side effects.

Combining Medication with Therapy

While medications can be effective, they often work best when combined with therapy, such as cognitive-behavioral therapy (CBT). Therapy can help you develop coping strategies, address underlying issues, and build resilience against mood swings.


Mood stabilizers are a vital tool in managing mood disorders and maintaining emotional stability. By understanding how these medications work, being aware of potential side effects, and adhering to your treatment plan, you can take an active role in your mental health care. Some mood stabilizers require monitoring their levels, so blood test is needed and will be scheduled by your provider. Always work closely with your healthcare provider to ensure your treatment is tailored to your needs, and never hesitate to ask questions or express concerns about your medication. Your health and well-being are a collaborative effort between you and your healthcare team.


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